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在免疫应答过程中，末梢血Ｔ细胞发育成功能不同的亚群，这些亚群通过分泌特殊的细胞因子介导细胞免疫应答和调节体液免疫应答。最近资料表明，一直被认为是单纯的细胞毒细胞的ＣＤ８￣＋Ｔ细胞在免疫应答中起积极的作用。本文中ＭｉｋｅＫｅｍｅｎｙ及其同事提出。存在着功能不同的ＣＤ８￣＋Ｔ细胞亚群，它们产生不同组合的细胞因子。并在决定ＣＤ４￣＋Ｔ细胞产生细胞因子的类型及Ｂ细胞表达免疫球蛋白的表型方面起重要作用。
During the immune response, peripheral blood T cells develop distinctly different subsets that mediate a cellular immune response and regulate the humoral immune response by secreting specific cytokines. Recent data indicate that CD8 + T cells, which have long been considered as pure cytotoxic cells, play an active role in the immune response. This article MikeKemeny and colleagues proposed. There are different subsets of CD8 + T cells that produce different combinations of cytokines. And plays an important role in determining the types of cytokines produced by CD4 ~ + T cells and the phenotype of immunoglobulin expressed by B cells.