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糖尿病肾病是糖尿病主要的并发症,已成为终末期肾脏病的主要病因之一。糖尿病合并肾脏损害有很大比例是非糖尿病性肾脏疾病,两者的治疗和预后明显不同,因此早期诊断对改善预后尤为重要。综合应用年龄、糖尿病病程、糖尿病视网膜病变、血压、血糖等临床指标有助于两者的鉴别诊断及判断预后,但单纯应用临床指标仍存在一定局限性,对怀有疑问的病例仍需依靠肾活检进行确诊。新型生物标志物的临床应用价值还须进一步验证。
Diabetic nephropathy is a major complication of diabetes and has become one of the major causes of end stage renal disease. A large proportion of patients with diabetic nephropathy have non-diabetic renal disease. The treatment and prognosis of the two are significantly different, so early diagnosis is particularly important for improving prognosis. Comprehensive application of age, duration of diabetes, diabetic retinopathy, blood pressure, blood glucose and other clinical indicators contribute to the differential diagnosis and prognosis of the two, but the simple application of clinical indicators there are still some limitations, the suspect cases still need to rely on the kidney Biopsy confirmed. The clinical value of new biomarkers needs to be further verified.