Design,synthesis,and insecticidal bioactivities evaluation of pyrrole-and dihydropyrrole-fused neoni

来源 :Chinese Chemical Letters | 被引量 : 0次 | 上传用户:shinobu1314
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Chlorothiazole ring,as a substituted heterocycle,frequently occurred in structures of various insecticides,and brought positive effect on bioactivity.In purpose to find novel neonicotinoids,a series of pyrrole-and dihydropyrrole-fused neonicotinoid analogs containing chlorothiazole ring were synthesized for the first time.Results of the following biological assays showed that compounds 5a-c achieved good insecticidal activity against Aphis craccivora,and compound 5h exhibited good activity against Nilaparvata lugens. Chlorothiazole ring, as a substituted heterocycle, frequently occurred in structures of various insecticides, and brought positive effect on bioactivity. Purpose to find novel neonicotinoids, a series of pyrrole-and dihydropyrrole-fused neonicotinoid analogs containing chlorothiazole ring were were for the first time . Results of the following biological assays showed those compounds 5a-c achieved good insecticidal activity against Aphis craccivora, and compound 5h exhibited good activity against Nilaparvata lugens.
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