作者用松鼠猴(Saimiri sciureus)模型,观察感染肺炎克雷伯氏菌后引起大叶性肺炎的临床、病理及一些生化反应。用体重0.5—1公斤的松鼠猴,气管内接种600—800个活菌(约1LD_(50)),约24小时后发生大叶性肺炎。感染的16只猴,分为四组,在5、24、30和48小时分别杀死一组,作病理学和组织内细菌浓度的检查。另15只猴分为三组, The authors used the Saimiri sciureus model to observe the clinical, pathological and biochemical reactions of lobar pneumonia after infection with Klebsiella pneumoniae. Mice weighing 0.5-1 kg were used to inoculate 600-800 viable cells (about 1 LD_ (50)) intratracheally and lobar pneumonia occurred about 24 hours later. Sixteen infected monkeys were divided into four groups and killed at 5, 24, 30, and 48 hours, respectively, for examination of pathology and bacterial concentration in the tissues. The other 15 monkeys were divided into three groups,