胃癌是世界范围内发病率和死亡率最高的上消化道恶性肿瘤。研究发现,早期胃癌患者术后的5年生存率可达90%以上,而进展期胃癌患者术后的5年生存率仅为20%[1]。为提高胃癌患者的生存率,对癌前病变和早期胃癌进行筛查和精确诊断至关重要。传统的白光内镜对早期胃癌的诊断仍存在特异度和灵敏度不足的缺点,不能准确诊断胃癌及癌前状态[2]。分子影像的出现和发展则为解决这些临床难题提供了新的技术手段。分子影像技术能够 Gastric cancer is the highest incidence and mortality of upper gastrointestinal cancer in the world. The study found that patients with early gastric cancer after 5-year survival rate of up to 90%, while patients with advanced gastric cancer 5-year survival rate was only 20% [1]. To improve the survival rate of patients with gastric cancer, precancerous lesions and early gastric cancer screening and accurate diagnosis is essential. The traditional white light endoscopy diagnosis of early gastric cancer there is still the shortcomings of lack of specificity and sensitivity, can not accurately diagnose gastric cancer and precancerous conditions [2]. The emergence and development of molecular images provide new technical means to solve these clinical problems. Molecular imaging technology can