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为探讨Ｂｏｒｎａ病病毒与人类精神疾病的关系，采用套式逆转录酶／聚合酶链反应技术检测７２例精神病病人和４０名健康献血者周围血单核细胞的Ｂｏｒｎａ病病毒ｐ２３基因片段。结果显示，精神分裂症组的ｐ２３阳性检出率（９．４％）稍高于健康对照组（７．５％），但差异无显著性；双相情感障碍组的阳性检出率（２１．１％）明显高于健康对照组（Ｐ＜０．０５）。提示人类双相情感障碍可能与Ｂｏｒｎａ病病毒感染有关。
In order to investigate the relationship between Borna disease virus and human mental diseases, 72 cases of psychiatric patients and 40 healthy blood donors peripheral blood mononuclear cells of Borna virus p23 gene fragment were detected by nested reverse transcriptase / polymerase chain reaction. The results showed that the positive rate of p23 in the schizophrenia group (9.4%) was slightly higher than that in the healthy control group (7.5%), but the difference was not significant. The positive rate of p23 .1%) was significantly higher than the healthy control group (P <0.05). Suggesting that human Bipolar disorder may be related to Borna disease virus infection.