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目的分析重症手足口病患儿的药物治疗情况,促进临床合理用药。方法收集赣州市妇幼保健院2016年1-6月收治的重症手足口病患儿57例,其中手足口病重症患儿重型(第2期)54例,手足口病重症患儿危重型(第3期)3例,对患儿行药物治疗情况进行分析。结果抗病毒药物使用率为100.00%,主要品种为利巴韦林、重组人干扰素α-2b等;抗菌药物使用率14.03%,主要品种为头孢硫脒、阿莫西林克拉维酸钾等;其他治疗药物主要为甲泼尼龙注射液、丙种球蛋白等。57例患儿均好转、治愈出院。结论赣州市妇幼保健院重症手足口病患儿的药物治疗总体合理、规范,但丙种球蛋白、糖皮质激素等药物的规范使用有待加强。
Objective To analyze the drug treatment of severe hand-foot-mouth disease in children and promote the rational use of medicine. Methods Fifty-seven children with severe hand-foot-mouth disease admitted from January to June 2016 in Ganzhou MCH hospital were enrolled. Among them, 54 cases were severe type 2 (HFMD), HFMD severe type 3) 3 cases of children with drug treatment analysis. Results The usage of antiviral drugs was 100.00%. The main varieties of ribavirin were ribavirin and recombinant human interferon α-2b. The antibacterials utilization rate was 14.03%. The main varieties were cefathiamidine, amoxicillin and clavulanate, Other treatment drugs mainly methylprednisolone injection, gamma globulin and so on. 57 cases were improved, cured and discharged. Conclusion The treatment of severe hand-foot-mouth disease in Ganzhou MCH hospital is generally reasonable and standardized. However, the standardized use of drugs such as gamma-globulin and glucocorticoid need to be strengthened.