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目的:探讨鼻腔NK/T细胞淋巴瘤的临床病理特征及影响预后的因素。方法:分析62例鼻腔NK/T细胞淋巴瘤的临床资料、病理特征、治疗和生存情况。结果:62例患者总的5年生存率为63.5%。单因素分析显示,年龄、穿孔、B症状、分期、Hb浓度、血清乳酸脱氢酶水平、瘤细胞大小、累及部位数量、血管浸润和治疗方式与预后关系密切(P<0.05或P<0.01);多因素分析显示,Hb浓度、瘤细胞大小和治疗方式是该病独立的预后因素(P<0.01或P<0.05)。结论:Hb浓度、瘤细胞大小和治疗方式是鼻腔NK/T细胞淋巴瘤主要的预后因素。
Objective: To investigate the clinicopathological features and prognostic factors of nasal NK / T cell lymphoma. Methods: The clinical data, pathological features, treatment and survival of 62 cases of nasal NK / T cell lymphoma were analyzed. Results: The overall 5-year survival rate of 62 patients was 63.5%. Univariate analysis showed that age, perforation, B symptoms, staging, Hb concentration, serum lactate dehydrogenase level, tumor size, number of involved sites, vascular invasion and treatment were closely related to prognosis (P <0.05 or P <0.01) Multivariate analysis showed that Hb concentration, tumor size and treatment were independent prognostic factors (P <0.01 or P <0.05). Conclusion: Hb concentration, tumor size and treatment are the main prognostic factors of nasal NK / T cell lymphoma.