INTRODUCTIONrnOsteoporosis is the most common metabolic bone disorder globally, causing low trauma fractures that lead to significant morbidity and mortality. Especially in high-income countries, osteoporotic fractures lead to a substantial loss of healthy life-years in older adults.1 Osteoporosis is characterized by impaired bone quality and/or reduced bone mass, resulting from an imbalance between bone formation and resorption. Noninvasive diagnosis of osteoporosis currently relies heavily on measurement of bοne mineral density (BMD) by dual energy X-ray absorptio-metry (DXA), which is the most widely used predictor of osteoporotic fractures.