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本实验的目的是研究不同硒含量的饲料对大鼠的毒性,以期为确定安全补硒剂量及制订食品中硒的卫生标准提供科学依据。实验分为对照组、不同水平亚硒酸钠、不同水平湖北高硒玉米组,共8组。饲养16～18周。结果发现饲料硒水平近似的条件下(4μg/g,2μg/g),吃高硒玉米的动物血硒远远高于吃亚硒酸钠的动物。血硒量前者均分别为后者的2倍(雌性)和4倍(雄性),肝和肾硒前者也高于后者。但动物出现肝脏病变的剂量(4μg/g)相似。因此,认为2.0μg/g硒还是安全的,而4.0μg/g以上就有引起肝脏病变的可能。
The purpose of this experiment is to study the toxicity of different selenium feed on rats, with a view to provide a scientific basis for determining the safe dose of selenium and formulating health standards of selenium in food. The experiment was divided into control group, different levels of sodium selenite, different levels of high selenium corn group, a total of 8 groups. Raise 16 to 18 weeks. The results showed that the selenium levels of feed (4μg / g, 2μg / g), eat high-selenium corn selenium far higher than the animals eat sodium selenite. The former blood selenium were the former two times (female) and four times (male), liver and kidney selenium former than the latter. However, the dose of animal liver lesions (4 μg / g) was similar. Therefore, 2.0 μg / g selenium is considered safe, while 4.0 μg / g or more has the potential to cause liver lesions.