多发性骨髓瘤是一种涉及合成抗体的浆细胞恶性增殖性疾病。Bence-Jones(1847)首先发现本病尿中的异常蛋白质,Rutizky(1873)将本病命名为多发性骨髓瘤。本病除异常蛋白质引起全身多系统病变外,还有明显的眼部表现。其发病率约为3:100000,且随年龄而增加。男女发病率相等,黑人比白人更多见。 Multiple myeloma is a plasma cell malignant proliferative disease involving the synthesis of antibodies. Bence-Jones (1847) first found abnormal urine protein in the disease, Rutizky (1873) named the disease multiple myeloma. In addition to the disease caused by abnormal protein systemic multiple system lesions, there are obvious ocular manifestations. Its incidence is about 3: 100,000, and increases with age. The incidence of men and women are equal, more common in blacks than in whites.