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目的探讨影响外科治疗食管鳞状细胞癌预后的危险因素。方法选取2007年1月至2012年1月间行食管鳞状细胞癌根治术患者115例,收集入选患者的临床资料和随访资料,对患者的主要预后因素进行回顾性分析。结果单因素分析显示肿瘤长度、有无淋巴结转移、淋巴结转移区域数、临床分期、病变浸润深度对患者预后有显著性影响(P<0.05);多因素分析显示肿瘤长度、淋巴结转移区域数和病变浸润深度的相对危险度分别为1.379、2.531、2.104。结论肿瘤长度、淋巴结转移区域数和病变浸润深度为鳞状细胞癌外科治疗预后的独立危险因素,应给予重视。
Objective To investigate the risk factors affecting the prognosis of surgical treatment of esophageal squamous cell carcinoma. Methods A total of 115 patients with esophageal squamous cell carcinoma undergoing radical resection between January 2007 and January 2012 were selected. The clinical data and follow-up data were collected and the main prognostic factors were retrospectively analyzed. Results Univariate analysis showed that tumor length, lymph node metastasis, lymph node metastasis, clinical stage and depth of invasion had significant effects on the prognosis of patients (P <0.05). Multivariate analysis showed that the length of tumor, the number of lymph node metastasis and the number of lesions The relative risk of invasion depth were 1.379, 2.531, 2.104 respectively. Conclusion The length of tumor, the number of lymph node metastasis and the depth of invasion of the tumor are independent risk factors for the prognosis of squamous cell carcinoma.