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本文对104例哮喘,55例哮支,58例毛细支气管炎患儿进行体外T、B细胞增殖反应,T细胞亚群,IgE及螨特异性IgE等多项免疫功能检查,同时进行临床随访研究。说明细胞免疫功能紊乱与T抑制细胞缺陷是产生高IgE的免疫病理基础,还分析了哮喘与哮支及毛细支气管炎间的相互关系及毛细支气管炎后易患哮喘的机理,得出了早期诊断(或识别)婴幼儿哮喘的临床与免疫学依据以及早期进行尘螨减敏治疗作为防治措施的可能性。
In this paper, 104 cases of asthma, 55 cases of bronchiolitis, 58 cases of bronchiolitis in children with T, B cell proliferation, T cell subsets, IgE and mite specific IgE and a number of immune function tests at the same time clinical follow-up study . Indicating that cellular immune dysfunction and T suppress cell defects are the immunopathological basis for the production of high IgE. The relationship between asthma and bronchiolitis and bronchiolitis is also analyzed, and the mechanism of asthma susceptibility to bronchiolitis is analyzed. Early diagnosis (Or identify) the clinical and immunological basis of infant asthma as well as the possibility of early desensitization treatment of dust mites as a preventative measure.