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目的探讨获得性免疫缺陷综合征(acquired immune defi ciency syndrome,AIDS,简称艾滋病)并发红皮病型药疹住院患者的临床特征及诊治方法。方法回顾性分析我院10例艾滋病并发红皮病型药疹住院患者的临床资料,对其一般资料、致敏药物、并发症、实验室检查、病程、疾病转归进行分析。结果住院的艾滋病并发红皮病型药疹10例患者多由抗病毒药、抗生素、抗结核药物引起,临床情况复杂,多伴有实验室检查异常和感染,病程较长,病死率较高,继发感染是主要的死因。结论艾滋病并发红皮病型药疹住院患者的临床情况复杂,病死率较高,合理使用糖皮质激素治疗,防治继发感染可降低病死率。
Objective To investigate the clinical characteristics and diagnosis and treatment of acquired immune defciency syndrome (AIDS) patients with erythrodermic eruption. Methods The clinical data of 10 hospitalized patients with AIDS and erythrodermic eruption were retrospectively analyzed. The general information, sensitization drugs, complications, laboratory tests, course of disease and disease outcome were analyzed. Results 10 cases of AIDS patients with erythrodermic drug eruption were mostly caused by antiviral drugs, antibiotics and anti-tuberculosis drugs. The clinical situation was complicated with many laboratory abnormalities and infections. The disease duration was longer and the case fatality rate was higher. Secondary infection is the leading cause of death. Conclusions The clinical situation of hospitalized patients with AIDS complicated with erythrodermic edema is complicated and the mortality rate is high. Rational use of glucocorticoid treatment and prevention and treatment of secondary infection can reduce the mortality.