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局部复发是头颈癌治疗失败的主要原因,所以局部控制率常常成为关注的焦点。然而,约近15%的患者出现远处转移。该研究通过单中心18年的临床回顾分析,旨在评估与远处转移发生的相关因素。评估指标包括远处转移的发生率,局部复发与时间的相关性,采用Kaplan-Meier法分析远处控制率,单因素分析包括病理、病因、手术、发病部位、肿瘤分化程度、治疗方式和局部控制率。结果:1022例患者中,141(13.8%)例出现远处转移,涉及283个部位。治疗后1、2、5、10年远处控制率分别为88%、84%、
Local recurrence is the main reason for the failure of head and neck cancer treatment, so the local control rate is often the focus of attention. However, about 15% of patients have distant metastases. The study was based on a 18-year single-center clinical review to assess factors associated with distant metastases. The evaluation indicators included the incidence of distant metastasis, the correlation between local recurrence and time, and the distant control rate by Kaplan-Meier analysis. The univariate analysis included pathology, etiology, operation, site of disease, degree of tumor differentiation, treatment mode and local Control rate. Results: Among 1022 patients, 141 (13.8%) cases showed distant metastasis involving 283 sites. At 1, 2, 5 and 10 years after treatment, the remote control rates were 88% and 84% respectively,