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目的总结分析2型糖尿病患者糖尿病足(DF)的患病情况及相关危险因素,为临床治疗和预防DF提供依据。方法选择2型糖尿病患者189例为研究对象,根据病情分为DF组和非DF组,回顾分析其性别、年龄、病程、入院时血压、空腹血糖、餐后2h血糖、糖化血红蛋白、血肌酐、尿素氮,以及尿白蛋白、糖尿病肾病、糖尿病视网膜病变、周围神经病变等因素。结果 DF所占比例为15%。DF组与非DF组相比,病程、餐后2h血糖、糖化血红蛋白、血肌酐、尿素氮、尿白蛋白、糖尿病肾病、糖尿病视网膜病变、周围神经病变等因素差异均有统计学意义(P<0.05)。其中病程、糖尿病肾病、糖尿病视网膜病变、周围神经病变进入回归模型亦有统计学意义(P<0.05)。结论 2型糖尿病的病程、肾病、视网膜病变、周围神经病变是DF发生的独立危险因素。
Objective To summarize and analyze the prevalence of diabetes mellitus (DF) in type 2 diabetic patients and related risk factors, so as to provide evidence for clinical treatment and prevention of DF. Methods A total of 189 patients with type 2 diabetes mellitus (T2DM) were enrolled in this study. The patients were divided into DF group and non-DF group according to the disease. The gender, age, course of disease, blood pressure at admission, fasting blood glucose, 2h postprandial blood glucose, glycosylated hemoglobin, Urea nitrogen, and urinary albumin, diabetic nephropathy, diabetic retinopathy, peripheral neuropathy and other factors. Results DF accounted for 15%. DF group and non-DF group, the course of disease, 2h postprandial blood glucose, glycosylated hemoglobin, serum creatinine, urea nitrogen, urinary albumin, diabetic nephropathy, diabetic retinopathy, peripheral neuropathy and other differences were statistically significant (P < 0.05). Among them, the course of disease, diabetic nephropathy, diabetic retinopathy and peripheral neuropathy also entered the regression model with statistical significance (P <0.05). Conclusion The course of type 2 diabetes, nephropathy, retinopathy and peripheral neuropathy are independent risk factors for DF.