论文部分内容阅读
自40～50年代开始化学疗法以来,结核病疫情明显下降。然而由于结核菌的某些生物学特性,需要长疗程用药,病人往往不能坚持服药,以致过早停药或不规则用药,因而治疗失败,复发较多。1965年利福平(R)问世,使化疗时限由1～1.5年缩短至6～9月,并能保持同样良好的效果。短程化疗是基于结核病灶内的不同菌群对药物敏感性不同,联合使用杀、灭菌剂尽快杀灭各类菌群,痰菌阴转快,治愈率高,复发率低,减少医疗开支和药物副作用,由于疗程缩短,病人易于坚持用药,为结核病化疗领域又一革新。现就短程化疗与结核菌
Since the beginning of chemotherapy in the 40s and 50s, the epidemic of tuberculosis has dropped significantly. However, due to some biological characteristics of TB, long courses of medication are required and patients often can not insist on medication, which leads to premature withdrawal or irregular medication. Therefore, treatment fails with more recurrence. The advent of rifampicin (R) in 1965 shortened the duration of chemotherapy from 1.5 to 6 months and maintained the same good results. Short-range chemotherapy is based on different flora within the tuberculosis drug sensitivity, combined use of killing, sterilization agents to kill all kinds of bacteria as soon as possible, sputum Yin Yin fast, high cure rate, low recurrence rate, reduce medical expenses and Drug side effects, due to shortened course of treatment, the patient easy to adhere to medication, another innovation for the tuberculosis chemotherapy. Now on short-course chemotherapy and tuberculosis