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应用冠脉结扎技术和生物测定法,观察急性心力衰竭(HF)大鼠心房肌提取物(AE)中心房钠尿因子(ANF)活性的改变.结果提示,急性HF时心房ANF含量和(或)活性的改变与慢性HF时有差别,心房肌肥大可能通过增加ANF的合成、贮存和释放过程而起到重要的代偿作用
The changes of ANF activity in the atrial myocardium extract (AE) of rats with acute heart failure (HF) were observed by coronary artery ligation and bioassay.The results suggested that the ANF content and ) Changes in activity and chronic HF when there is a difference, atrial hypertrophy may increase ANF synthesis, storage and release process and play an important compensatory role