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心房颤动（房颤）是临床上最常见的持续性心律失常，可导致患者死亡率升高。胃食管反流是消化科的常见病症，是胃内容物反流入食管引起的不适症状和／或并发症。有研究报道胃食管反流可能会引起房颤。炎症、迷走神经刺激和慢性心房缺血可能是其中的重要机制，炎症反应和自主神经功能异常参与房颤和胃食管反流病的发生发展。本文结合国内外文献对房颤与胃食管反流间的关系及其可能机制进行综述。“,”Atrial fibrillation (AF)is the most common sustained arrhythmia which contributes to the increasing mortality risk in clinical practice.Gastroesophageal reflux disease(GERD)is commonly seen in the department of Gastroenterology.It refers to discomfortable symptoms and(or)complica-tions caused by the reflux of gastric contents into esophagus.It was reported that gastroesophageal re-flux may give rise to AF.Inflammation,vagal stimulation and chronic atrial ischemia may be impor-tant potential mechanisms;inflammatory responses and autonomic nervous dysfunction take part in the onset and development of AF and GERD.Based on correlative domestic and foreign references,this paper reviews the relationship between AF and GERD,and its possible mechanisms.