目的 :动脉粥样硬化可能是一些下腰痛患者的病因 ,腰骶区的血供不足可能导致下腰痛。方法 :对 10 0例年龄大于 5 0岁的严重下腰痛患者行前瞻性研究 ,通过影像学检查发现 19例患者存在腹主动脉钙化。这 19例患者经多学科会诊后行抗动脉粥样硬化治疗在内的综合治疗。结果 :19例患者随访了 1～ 2年 ,根据主观症状评估示 13例疗效满意 ,随访检查示患者的腹主动脉钙化无明显变化。结论 :动脉粥样硬化是引起下腰痛的可能病因之一 ,但下腰痛史可能是多因素作用的结果。 AIM: Atherosclerosis may be the cause of some low back pain patients. Lack of blood supply to the lumbosacral region may result in lower back pain. Methods: A prospective study of 10 0 patients with severe low back pain greater than 50 years old was performed. The abdominal calcification of the abdominal aorta was found in 19 patients by imaging examination. These 19 patients underwent multidisciplinary consultations after anti-atherosclerotic treatment, including comprehensive treatment. Results: Nineteen patients were followed up for 1 to 2 years. According to the subjective symptom evaluation, 13 cases showed satisfactory results. Follow-up examination showed no significant changes of abdominal aortic calcification. Conclusion: Atherosclerosis is one of the possible causes of lower back pain. However, the history of lower back pain may be the result of multiple factors.