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红细胞膜上具有免疫粘附作用的C_(3b)受体,它能够吸附并清除血液循环中的免疫复合物。本文应用简易的红细胞C_(3b)受体花环试验与红细胞免疫复合物花环试验方法,对30例血液病患者的红细胞免疫功能进行了测定。结果表明,白血病患者,再障患者及自免贫患者C_(3b)受体花环率均明显降低,白血病患者免疫复合物花环率相对较高。本文对血液病患者红细胞免疫功能变化的机理及影响因素进行了初步探讨,提示红细胞免疫功能的测定可做为血液病患者治疗,预后的一个观察指标。
The erythrocyte membrane C_ (3b) receptor with immune adhesion, it can adsorb and remove immune complexes in the blood circulation. In this paper, erythrocyte immune function in 30 patients with hematological diseases was measured by the simple erythrocyte C_ (3b) receptor rosette assay and erythrocyte immune complex rosette assay. The results showed that the percentage of C_ (3b) receptor rosette in patients with leukemia, aplastic anemia and patients with aplastic anemia was significantly lower than that in patients with leukemia. The rate of rosette of immunocomplex in patients with leukemia was relatively high. In this paper, the mechanism and influencing factors of erythrocyte immune function in patients with hematological diseases were preliminarily discussed, which suggested that the determination of erythrocyte immune function could be used as an observation index for the treatment and prognosis of patients with hematological diseases.