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早在30年代初,Goldbatt 和 Euler 分别从人精液和绵羊精囊中分离到天然前列腺素(PG),但由于在组织中 PG 的含量很低,使对PG 的研究进行30年无多大进展。1957年 Berg-str(?)m 确定了 PGE 和 FGF 的化学结构后,对 PG 的生化、生理和药理等方面研究有了迅速发展,对 PG 在机体中的重要作用有了进一步认识。Samnelszon 等于1973年和1975年发现了 PG 内过氧化物和血栓烷(Throm-boxane,简称 TX),迎来了 PG 研究的新局
As early as the early 1930s, Goldbatt and Euler isolated natural prostaglandins (PGs) from human semen and sheep seminal vesicles, respectively, but little progress was made in the study of PG for 30 years due to the low level of PG in the tissues. After Berg-str (?) M determined the chemical structure of PGE and FGF in 1957, the research on biochemical, physiological and pharmacological aspects of PG has been rapidly developed, and the important role of PG in the body has been further recognized. Samnelszon is equivalent to discover PG and Thromboxane (TX) in 1973 and 1975, ushering in a new study of PG