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本文报告在1500例纤维胃镜检查和胃粘膜活检中发现胃粘膜肠上皮化生221例,检出率为14.1％。其检出率随年龄增长而增高,以50～59岁年龄组最多,好发于胃实部小弯侧。本组肠上皮化生病例均伴随慢性胃炎。在萎缩性胃炎中并发肠上皮化生26.4％,胃癌中占31.4％。胆汁返流和粘膜糜烂与其有一定的关系。本文对其中37例肠上皮化生进行近期随访复查,发现一例伴有肠上皮化生的萎缩性胃炎发生癌变,2例由重度肠上皮化生转变为轻度,4例有不同程度转轻,5例再找不到肠上皮化生,说明它也可逆转,但由于随访时间较短,还应定期追踪观察。
In this paper, 221 cases of gastroenteric intestinal metaplasia were found in 1500 cases of gastroscopy and gastric biopsy, and the detection rate was 14.1%. The detection rate increased with age, with the most in the 50-59 age group, and it occurred in the small curved side of the stomach. All cases of intestinal metaplasia in this group were associated with chronic gastritis. In atrophic gastritis, intestinal epithelial metaplasia was 26.4%, and gastric cancer accounted for 31.4%. Bile reflux and mucosal erosion have a certain relationship with it. In this paper, 37 cases of intestinal metaplasia were followed up for a short period of time. It was found that one case of atrophic gastritis with intestinal metaplasia was cancerous, 2 cases were changed from severe intestinal metaplasia to mild, and 4 cases had mild to moderate degrees. Intestinal epithelial metaplasia could not be found in 5 cases, indicating that it can also be reversed, but due to the short follow-up time, it should also be regularly tracked.