卵巢早衰是由多种病因所致的卵巢功能衰竭,病理生理表现较复杂,根据病因可通过多种方式建立动物模型,如半乳糖模型、免疫模型、化疗药物模型、初生小鼠胸腺切除模型、高血压模型等。本文对卵巢早衰动物模型的多种造模法进行了文献综述。 Ovarian premature ovarian failure is caused by a variety of causes of ovarian failure, the pathophysiological performance is more complex, according to the etiology of animal models can be established through a variety of ways, such as galactose model, immune model, chemotherapeutic drug model, neonatal thymus resection model, Hypertension model and so on. This article reviews the literature on various modeling methods for animal models of premature ovarian failure.