心力衰竭是大多数心血管疾病的终末阶段,其原因有心肌受损、心室负荷过度、心室充盈障碍以及心律失常,最终导致心室泵功能低下,其病死率高,预后不良。尽管在治疗心力衰竭方面我们已经有血管紧张素转换酶抑制剂(ACEI)和β肾上腺素能受体阻断剂,但慢性心力衰竭仍然是全世界发病和死亡的主要原因之一。我们仍然需要寻找更好的治疗方案,尤其部分 Heart failure is the terminal stage of most cardiovascular diseases, due to myocardial damage, excessive ventricular load, ventricular filling disorders and arrhythmias, eventually leading to poor ventricular pump function, high mortality and poor prognosis. Although we already have ACE inhibitors and beta adrenergic receptor blockers in the treatment of heart failure, chronic heart failure remains one of the leading causes of morbidity and mortality in the world. We still need to find better treatment options, especially in parts