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目的调查和分析个旧市伤寒副伤寒发病的危险因素,为防控提供科学依据。方法采用病例对照的研究方法,在近年来云南省伤寒副伤寒报告发病率较高的个旧市,选取血培养确诊病例50例,对照100例,采用问卷收集资料。用EpiData 3.1建立数据库,用SPSS 22.0统计软件对数据进行分析,单因素分析采用χ~2检验,多因素分析采用非条件logistic回归分析。结果发病前2周是否经常吃米线(OR=5.784,95%CI:1.288~25.969)和病前2周吃过冷饮(OR=4.593,95%CI:1.790~11.781)是伤寒副伤寒发病的危险因素。结论个旧市伤寒副伤寒高发主要与不安全的食物有关,今后应加强食品卫生的监管力度和对群众的宣传教育力度,降低伤寒副伤寒的发病率。
Objective To investigate and analyze the risk factors of the pathogenesis of typhoid and paratyphoid fever in Gejiu and to provide a scientific basis for prevention and control. Methods A case-control study was conducted. In Gejiu City, which reported a higher incidence of typhoid and paratyphoid fever in Yunnan in recent years, 50 cases of blood culture were selected and 100 cases of control were selected. Data were collected by questionnaire. EpiData 3.1 was used to establish the database. SPSS 22.0 statistical software was used to analyze the data. Univariate analysis was used for Chi-square test and multivariate analysis was used for non-conditional logistic regression analysis. Results The incidence of typhoid and paratyphoid fever was significantly higher in the two weeks before the onset of illness (OR = 5.784, 95% CI: 1.288 to 25.969) and two weeks before the onset of illness (OR = 4.593, 95% CI: 1.790 to 11.781) factor. Conclusions Gejiu’s typhoid and paratyphoid fever are mainly related to unsafe food. In the future, the supervision of food hygiene and publicity and education of the masses should be strengthened to reduce the incidence of typhoid and paratyphoid fever.