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目的 比较速可眠（ＳＥＣ）、三唑仑（ＴＺＬ）、褪黑素（ＭＬＴ）催眠的电生理特征，探讨其对脑功能防护的可能性。 方法 在模拟歼－６ 飞机噪声干扰环境中（１５０ Ｈｚ、９５ ｄＢ），观察上述三种药物对８ 名健康男性青年志愿者（１８～２０ 岁）多导睡眠图（ＰＳＧ）指标的影响，即对醒觉时间（ａｗ ａｋｅ ｔｉｍ ｅ，ＡＴ）、睡眠潜时（ｓｌｅｅｐ ｌａｔｅｎｃｙ， ＳＬ）、实际睡眠时间（Ａｃｔｕａｌｓｌｅｅｐ ｔｉｍ ｅ， ＡＳＴ），睡眠效率（ｓｌｅｅｐ ｅｆｆｉ－ｃｉｅｎｃｙ， ＳＥ）的影响，并结合认知操作综合比较其催眠效果和对脑功能的潜在防护作用。 结果 ＳＥＣ、ＴＺＬ组的ＡＴ未见明显增加，ＡＳＴ 未见明显减少，而ＭＬＴ组的ＡＴ、ＡＳＴ 受环境噪声干扰较大。ＳＥ比较：ＳＥＣ＞ ＴＺＬ＞ ＭＬＴ；ＳＬ比较：ＴＺＬ＜ ＳＥＣ＜ ＭＬＴ。认知操作检查：ＳＥＣ、ＴＺＬ两组的反应时（ＲＴ）与基础组无显著性差异（Ｐ＞ ０．０５），认知操作效率＞ ８５％ ，ＭＬＴ组的ＲＴ 与安慰剂组无显著性差异（Ｐ＞ ０．０５），认知操作效率＜ ７０％ 。 结论 ＳＥＣ、ＴＺＬ可通过减少ＡＴ，缩短ＳＬ，增加ＡＳＴ，提高ＳＥ；ＭＬＴ对上述指标的影响不显著。ＴＺＬ的催眠诱导?
Objective To compare the electrophysiological characteristics of hypnosis (SEC), triazolam (TZL) and melatonin (MLT), and to explore the possibility of their protective effect on brain function. Methods The effects of three drugs on polysomnography (PSG) in 8 healthy male volunteers (18 ~ 20 years old) were observed in a simulated environment of noise disturbance of F -6 aircraft (150 Hz, 95 dB) (AT), sleep latency (SL), actual sleep time (AST), sleep efficiency (SE), and combined with the recognition Know the operation of a comprehensive comparison of its hypnotic effect and potential protective effect on brain function. Results AT, TZL group AT no significant increase in AST no significant reduction, while MLT group of AT, AST interference by environmental noise. SE comparison: SEC> TZL> MLT; SL comparison: TZL 0.05), cognitive efficiency> 85%, no significant difference between MLT group and placebo group Difference (P> 0.05), cognitive efficiency <70%. Conclusions SEC and TZL can reduce AT, shorten SL, increase AST, and improve SE; MLT has no significant effect on these indexes. TZL hypnosis induced?