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目的:分析采用银杏达莫注射液治疗2型糖尿病脑梗死的临床疗效及其对血清C-反应蛋白(CRP)与可溶性细胞间黏附分子(sICAM-1)的影响。方法:选取2015年4月至2016年4月汕头市潮阳区人民医院接收并治疗的2型糖尿病脑梗塞患者62例,每组31例,按临床随机数表法分为两组,每组31例,对照组行常规基础治疗,观察组则联合银杏达莫注射液治疗,对比分析两组患者治疗效果。结果:观察组治疗后日常生活能力量表(ADL)评分上升程度优于对照组(P<0.05);观察组治疗后神经功能缺损评分量表(NIHSS)、CRP、s ICAM-1水平下降程度优于对照组(P<0.05);且观察组治疗后的总有效率高于对照组(P<0.05)。结论:采用银杏达莫注射液治疗2型糖尿病脑梗塞的临床疗效显著,有利于降低炎性因子。
OBJECTIVE: To analyze the clinical efficacy of Yin Xing Damo injection in the treatment of type 2 diabetic cerebral infarction and its effect on serum C-reactive protein (CRP) and soluble intercellular adhesion molecule (sICAM-1). Methods: From April 2015 to April 2016, 62 patients with type 2 diabetes mellitus received cerebral infarction in Chaoyang District People’s Hospital of Shantou City, 31 patients in each group. The patients were divided into two groups according to the randomized clinical trial Cases, the control group underwent routine basic treatment, the observation group was combined with gingko Damo injection treatment, comparative analysis of two groups of patients with treatment. Results: The scores of ADL in observation group were better than those in control group after treatment (P <0.05). The levels of NIHSS, CRP, s ICAM-1 in observation group decreased (P <0.05). The total effective rate of the observation group after treatment was higher than that of the control group (P <0.05). Conclusion: The clinical efficacy of Yinxingdamo injection in the treatment of type 2 diabetic cerebral infarction is significant, which is helpful to reduce the inflammatory factors.