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本文探讨了糖尿病患者的胃排空能力与植物神经功能的关系。研究对象是6名健康人和48名伴神经功能障碍的糖尿病患者。通常以心电图R-R间期的变动系数CV_R-R表示副交感神经的功能(植物功能测定的主要内容),胃排空能力采用原沢氏标准法,即通过醋氨酚法测试。在实验前一天晚上禁食,当天停用全部药物,让受检者将加温后的OKUNOSU-A200ml与醋氨酚(acetaminophen)1.5g的混合物于早八点三十分服下(2～3分钟服完),在服用前及服后15′、30′、45′、60′依次抽血测定血中醋氨酚的浓度。结果6名健康人血中醋氨酚的值在45分钟前呈直线增加,45′～60′达到顶峰。以45分时的数值作为胃排空能力的指标,伴轻度末梢神经炎的糖尿病患者,胃排空较正常人稍慢,个别的较正常人快;伴重度末梢神经炎的糖尿病患者全部较正常人平均值稍低,胃排空的速度较
This article explores the relationship between gastric emptying and autonomic function in diabetic patients. The subjects were six healthy individuals and 48 diabetic patients with neurological dysfunction. Usually ECG R-R interval coefficient of variation CV_R-R said the function of parasympathetic function (the main content of plant function test), gastric emptying ability using the original standard method, that is tested by acetaminophen test. Fasting the night before the experiment, all the drugs were discontinued the same day, so that the subjects in the warm OKUNOSU-A200ml and acetaminophen 1.5g mixture in the early eight thirty under the service (2-3 Minute service), before taking and after serving 15 ’, 30’, 45 ’, 60’ followed by blood to determine the concentration of acetaminophen in the blood. Results The values of acetaminophen in 6 healthy volunteers increased linearly 45 min before reaching the peak at 45 ’~ 60’. The value of 45 minutes as an indicator of gastric emptying capacity, with mild peripheral neuritis in diabetic patients, gastric emptying slower than normal, some individuals faster than normal; diabetic patients with severe peripheral neuritis than normal Slightly lower average, gastric emptying speed