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李福山:第一军医大学学报1983;3(2):138。对收治22例急性、亚急性重症肝炎通过临床观察和有关文献提出早期诊断的体会:一、早期临床表现:从急性肝炎发展至急性,亚急性重症肝炎短者数小时,长者数周。重症肝炎患者黄疸发展迅速、疲倦感明显。发热、脉快,特别是睡眠节律改变或反应迟钝常为重症肝炎的先兆。22例中,有8例出现性格、情绪异常,智力障碍和扑翼祥震颤。二、有助于早期诊断的实验室检查:(1)血清胆红质开始增加,血清转氨酶反而下降,即胆酶分离现象;(2)间接胆红质相对增加;(3)血清白蛋白减少;(4)胆
Li Fushan: Journal of First Military Medical University 1983; 3 (2): 138. On the treatment of 22 cases of acute, subacute severe hepatitis through clinical observation and literature to make early diagnosis: First, the early clinical manifestations: the development of acute hepatitis to acute, subacute severe hepatitis a few short hours, the elderly for several weeks. Severe hepatitis patients with rapid development of jaundice, significant sense of fatigue. Fever, pulse fast, especially changes in sleep rhythm or unresponsiveness often a harbinger of severe hepatitis. Of the 22 cases, 8 showed symptoms, mood disorders, mental retardation and flapping wing tremor. Second, to help early diagnosis of laboratory tests: (1) serum bilirubin began to increase serum transaminase but decreased, the phenomenon of bile enzyme separation; (2) a relative increase in indirect bilirubin; (3) decreased serum albumin ; (4) Guts