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HNK_1~+(Leu7~+)细胞是具有自然杀伤(NK)或杀伤功能的一群大颗粒淋巴细胞。它们可以同时表达T细胞抗原、单核细胞抗原或Leu 11和VEP13抗原。Leu7~+细胞亚群表现不同的细胞毒能力,并且可出现在NK细胞分化的不同阶段。具有单核细胞表现型的Leu7~+细胞较T细胞表现型的Leu7~+细胞有更强的NK细胞功能,而在Leu7~+细胞亚群中同时表达Leull或VEP13抗原的Leu7~+细胞具有最强的细胞毒效应。此外,在形态
HNK_1 ~ + (Leu7 ~ +) cells are a group of large granule lymphocytes with natural killer (NK) or killing function. They can simultaneously express T cell antigens, monocyte antigens or Leu 11 and VEP13 antigens. Leu7 ~ + cell subsets exhibit different cytotoxicities and can occur at different stages of NK cell differentiation. Leu7 ~ + cells with monocyte phenotype had stronger NK cell function than Leu7 ~ + cells with T cell phenotype, whereas Leu7 ~ + cells with Leull or VEP13 antigen expressed simultaneously in Leu7 ~ + cell subpopulation had The strongest cytotoxic effect. In addition, in morphology