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目的比较恩再适或联合伐昔洛韦治疗带状疱疹的效果及安全性。方法将带状疱疹患者50例随机分为恩再适组和常规组各25例,两组患者均使用伐昔洛韦治疗10 d及维生素B_1、B_(12)等基础治疗15d,恩再适组加用恩再适36 U/日肌内注射5d。观察2组患者皮损控制情况、疼痛改善情况及后遗神经痛的发病率。结果恩再适组疼痛减轻时间(6.2±3.6)日和疼痛消失时间(15.1±5.6)日均较常规治疗组(11.3±5.6,25.3±7.9)日明显缩短,差异有统计学意义(P<0.05)。结论带状疱疹采用伐昔洛韦治疗时,加用恩再适可缩短疼痛时间,减低后遗神经痛的发病率。
Objective To compare the efficacy and safety of enzhu or combined valacyclovir in the treatment of shingles. Methods 50 cases of shingles were randomly divided into enzacyx group and conventional group of 25 cases, both groups were treated with valacyclovir 10 days and vitamin B_1, B_ (12) and other basic treatment for 15 days, En again Group plus grace and then fit 36 U / day intramuscular injection 5d. Skin lesions were observed in two groups of patients, the improvement of pain and the incidence of neuralgia. Results The average daily pain relief time (6.2 ± 3.6 days) and pain disappearance time (15.1 ± 5.6) in En Zuji group were significantly shorter than those in the conventional treatment group (11.3 ± 5.6,25.3 ± 7.9) days, with significant difference (P < 0.05). Conclusion When shuanciclovir is used in the treatment of shingles, it can be used to shorten the pain time and reduce the incidence of postherpetic neuralgia.