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目的观察药物左室减容术对扩张型心肌病疗效及对远期预后的影响。方法76例按入院先后顺序随机分为治疗组及对照组各38例,2组均给予抗心衰基础治疗,治疗组同时静脉加用大剂量扩血管、利尿剂、激素强化治疗,分别于治疗后第10d,28 d复查相关指标,观察疗效及并发症。周期性强化、维持,并随访。结果药物左室减容术在短期内心功能改善、心率减慢、心脏缩小程度及射血分数均优于对照组(P<0.05)。但并发症:电解质紊乱、血糖升高高于对照组。治疗组最长随访2.5年,无1例死亡及心脏重新扩大。结论药物左室减容术能迅速使扩大的心室缩小,改善心功能,提高生活质量。
Objective To observe the effect of drug-induced left ventricular volume reduction on dilated cardiomyopathy and its long-term prognosis. Methods Seventy-six patients were randomly divided into treatment group and control group with 38 cases in each group. The two groups were given basic treatment of anti-heart failure. In the treatment group, intravenous injection of high-dose vasodilator, diuretic and hormone therapy were given respectively. After the first 10d, 28d review the relevant indicators to observe the efficacy and complications. Periodically strengthen, maintain, and follow-up. Results The LV volume reduction technique improved heart function, reduced heart rate, decreased heart size and ejection fraction in the short term (P <0.05). However, complications: electrolyte imbalance, elevated blood sugar than the control group. In the treatment group, the longest follow-up was 2.5 years, none of them died and the heart was re-enlarged. Conclusions Drug LV volume reduction can rapidly reduce the enlarged ventricle, improve cardiac function and improve quality of life.