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目的评价不同时期妊娠高血压综合征(妊高征)子痫患者治疗方法对母婴结局的影响。方法回顾分析以1990年1月至1996年2月(第一阶段)和1996年3月至2002年4月(第二阶段)为两个阶段不同的临床处理措施对孕产妇病死率和围生儿病死率的影响。结果第一阶段治疗产前子痫患者42例,采取相对保守的治疗措施入院至分娩结束时间为16～126h,平均(26±12.4)h;剖宫产率为33.3%(14/42),孕产妇病死率14.3%(6/42),围生儿病死率为16.7%(7/42),产后子痫再次发作率为14.3%(6/42)。第二阶段采取相对积极的治疗措施治疗32例产前子痫患者,入院至分娩结束时间为1～6h,平均(2.4±0.8)h,剖宫产率为71.8%(23/32),孕产妇病死率为3.1%(1/32),围生儿病死率6.3%(2/32),产后硫酸镁使用率为96%(29/32),产后无再次抽搐发生。结论妊高征产前子痫患者应采取积极的治疗措施,在解痉、镇静的基础上,早期终止妊娠是降低母婴病死率、提高产科质量的有效措施。
Objective To evaluate the effect of treatment on eclampsia in pregnancy-induced hypertension syndrome (PIH) in different periods on maternal and infant outcome. Methods The clinical data of maternal mortality and perinatal morbidity from January 1990 to February 1996 (the first phase) and March 1996 to April 2002 (the second phase) were retrospectively analyzed. The impact of child mortality. Results In the first phase, 42 cases of preeclampsia were treated with relatively conservative treatment. The time from admission to delivery was 16-126 h (mean, 26 ± 12.4 h). The rate of cesarean section was 33.3% (14/42) Maternal mortality rate was 14.3% (6/42), perinatal mortality rate was 16.7% (7/42), postpartum eclampsia recurrence rate was 14.3% (6/42). The second phase to take relatively active treatment of 32 cases of preeclampsia patients, admission to delivery end time was 1 ~ 6h, mean (2.4 ± 0.8) h, cesarean section rate was 71.8% (23/32), pregnancy Maternal mortality was 3.1% (1/32), perinatal mortality was 6.3% (2/32), postpartum magnesium sulfate use was 96% (29/32), postpartum no convulsions. Conclusion Pregnancy-induced hypertension in pre-eclampsia patients should take active treatment measures. On the basis of antispasmodic and sedation, early termination of pregnancy is an effective measure to reduce maternal and infant mortality and improve the quality of obstetrics.