盐酸普鲁卡因注射液为常用的麻醉药。含量测定有银量法、非水滴定法、紫外分光光度法、交流示波极谱滴定等等。然而,盐酸普鲁卡因注射液不稳定,易水解生成对氨基苯甲酸(PABA),对其测定有干扰。美国药典(20版)采用加碱—氯仿提取PABA 消除干扰,再用紫外分光光度法测定,此法虽准确,但较繁琐。本文选用 Procaine hydrochloride injection for the commonly used anesthetics. Determination of the amount of silver method, non-water titration method, UV spectrophotometry, AC oscillometric polar titration and so on. However, procaine hydrochloride injection is unstable and easily hydrolyzed to form p-aminobenzoic acid (PABA), which has interference with its determination. The United States Pharmacopoeia (20 version) using alkali - chloroform extracted PABA eliminate interference, and then measured by UV spectrophotometry, although this method is accurate, but more complicated. This article selection