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氧化铈纳米粒子因其优异的催化活性而一直以来备受关注.它的催化性质来源于表面铈离子可以快速地进行Ce4+和Ce3+转变,能够根据环境很容易地接受或失去电子.长久以来,其应用均集中在工业催化方面.然而近年来,它被发现具有多种生物酶,如超氧化物歧化酶、过氧化氢酶、磷酸酶、过氧化物酶和氧化酶等的模拟活性,以及具有羟基自由基及氮氧化物自由基清除的能力.这些多重酶活性使其在生物方面有着众多极具前景的潜在应用价值.目前,在生物领域其已被开发用于生物检测、疾病诊断及治疗、药物载体及生物支架等方面.本文主要介绍其多种生物酶活性、活性原理,及在生物领域中的最新研究进展.
Due to its excellent catalytic activity, cerium oxide nanoparticles have attracted much attention because of their catalytic nature. Cerium ions can rapidly undergo Ce4 + and Ce3 + conversion and can easily accept or lose electrons depending on the environment. For a long time, cerium oxide Applications have focused on industrial catalysis, however, in recent years, it has been found to have mimicry activity of various biological enzymes such as superoxide dismutase, catalase, phosphatase, peroxidase and oxidase, Hydroxyl free radicals and nitrogen oxide free radical scavenging capacity of these multiple enzyme activity makes it has many biological potential of great potential value.Currently, it has been developed in the biological field for biological testing, disease diagnosis and treatment , Drug carriers and biological scaffolds, etc. This paper mainly introduces its various biological enzyme activity, activity principle, and the latest research progress in the field of biology.