患者，女，27岁。习惯性便秘3年。自述3～4日排便1次，干燥，量少，食欲不振，腹胀明显，月经周期正常。查体：腹平软，未见肠型及蠕动波，左下腹可触及肠内粪块，肠鸣音正常存在。做全消化道造影检查未见异常。考虑便秘为肠蠕动减慢所致。给予普瑞博思10mg口服，每日3次，五周 Patient, female, 27 years old. Habitual constipation 3 years. Read 3 to 4 days defecation 1, dry, less, loss of appetite, abdominal distension, menstrual cycle is normal. Physical examination: abdominal soft, no intestinal and peristaltic waves, the left lower quadrant can touch the intestine fecal block, bowel sounds normal existence. Do the whole digestive tract imaging examination no abnormalities. Consider constipation due to slowed bowel movements. Pregabalus given 10mg orally 3 times a day for five weeks