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目的:探讨妊娠期合并乙型肝炎病毒感染对妊娠结局的影响。方法:对2009年1月～2012年1月间在我院分娩的248例妊娠期肝炎孕妇的妊娠结局进行回顾性分析。结果:妊娠期合并乙型肝炎病毒感染的并发症主要包括:胎膜早破(21.8%)、胎儿窘迫(13.7%)、妊高征(12.9%)、早产(11.3%)、产后出血(10.1%),肝功能正常组孕妇的发生率显著低于肝功能异常组(P<0.05);肝功能正常组低体重儿以及新生儿窒息的发生率显著较低(P<0.05)。结论:妊娠期合并乙型肝炎病毒感染且肝功能异常对妊娠结局的影响较大,临床应重视此类病例的治疗。
Objective: To investigate the influence of pregnancy complicating hepatitis B virus infection on pregnancy outcome. Methods: The pregnancy outcomes of 248 gestational hepatitis pregnant women who were delivered in our hospital from January 2009 to January 2012 were analyzed retrospectively. Results: Complications of hepatitis B virus infection in pregnancy mainly included premature rupture of membranes (21.8%), fetal distress (13.7%), pregnancy induced hypertension (12.9%), preterm birth (11.3%), postpartum hemorrhage %). The incidence of pregnant women with normal liver function was significantly lower than that of normal liver function group (P <0.05). The incidence of asphyxia in normal liver function group was significantly lower than that in normal group (P <0.05). Conclusion: Pregnancy complicated with hepatitis B virus infection and abnormal liver function have a great influence on pregnancy outcome. Clinical treatment should pay attention to these cases.