疟疾血清学已有很长的历史。虽自1918年Pewny就已创用了沉淀试验,但同补体结合试验及黑素絮凝试验一样,都很少在疟疾的诊断和流行病学上实际应用。到六十年代早期,发现免疫萤光抗体技术后,疟疾血清学的研究才重新兴起。前十年所进行的大量研究,大大地增长了我们对测定和解释宿主在自然感染后的免疫反应的知识。除间接萤光抗体技术外,还发现了其他血清学和免疫学技术,如间接红细胞凝集试验、可溶性抗原萤 Malaria serology has a long history. Pewny has used sediment tests since 1918, but as with complement fixation tests and melanin flocculation tests, seldom used in the diagnosis and epidemiology of malaria. By the early 1960s, studies of malaria serology had only been revived after immunofluorescent antibody technology was discovered. Numerous studies conducted over the last ten years have greatly increased our knowledge of determining and explaining the host’s immune response after natural infection. In addition to indirect fluorescent antibody techniques, other serological and immunological techniques have also been discovered, such as indirect hemagglutination assays, soluble antigens