论文部分内容阅读
目的探讨冠心病不稳定型心绞痛采用阿托伐他汀联合通心络胶囊治疗的临床效果情况及对血脂的影响。方法选择2013年1月-2014年6月医院收治的冠心病不稳定型心绞痛患者160例,随机分为观察组和对照组各80例。对照组予阿托伐他汀治疗,观察组在对照组治疗基础上加用通心络胶囊治疗,比较2组临床效果、血脂水平及不良反应发生率。结果观察组总有效率为96.25%明显高于对照组的85.00%,差异有统计学意义(P<0.05)。2组血脂水平治疗前比较差异无统计学意义(P>0.05)。治疗后,2组TC、TG、LDL-C较治疗前明显降低,且观察组TC、TG、LDL-C较对照组明显降低,HDL-C较对照组高,差异有统计学意义(P<0.05)。治疗中观察组出现不良反应6例(7.50%),对照组出现不良反应5例(6.25%),2组比较差异无统计学意义(P>0.05)。结论阿托伐他汀联合通心络胶囊治疗冠心病不稳定型心绞痛临床疗效显著,血脂水平恢复正常,不良反应较少,值得临床推广应用。
Objective To investigate the clinical effect of atorvastatin combined with Tongxinluo capsule in the treatment of unstable angina pectoris and its effect on blood lipids. Methods From January 2013 to June 2014, 160 patients with coronary heart disease and unstable angina pectoris admitted to our hospital were randomly divided into observation group (80 cases) and control group (80 cases). The control group was treated with atorvastatin. The observation group was treated with Tongxinluo capsule on the basis of the control group. The clinical effect, blood lipid level and the incidence of adverse reactions in the two groups were compared. Results The total effective rate was 96.25% in the observation group was significantly higher than 85.00% in the control group, the difference was statistically significant (P <0.05). There was no significant difference between the two groups before treatment (P> 0.05). After treatment, the levels of TC, TG and LDL-C in two groups were significantly lower than those before treatment, and the levels of TC, TG and LDL-C in the observation group were significantly lower than those in the control group and HDL-C was higher than the control group (P < 0.05). There were 6 adverse reactions (7.50%) in the observation group and 5 (6.25%) adverse reactions in the control group. There was no significant difference between the two groups (P> 0.05). Conclusions Atorvastatin combined with Tongxinluo Capsule in the treatment of unstable angina pectoris has significant clinical effects, blood lipid levels returned to normal, with fewer adverse reactions, which is worthy of clinical application.