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本文报告了1993年河北省在抢救有机磷农药急性中毒中,推广应用了抢救新技术,即以解磷针为主的新疗法,并与以大量应用阿托品为主的传统疗法进行了比较。解磷针是军事医学科学院毒物药物研究所研制的一种复方制剂,内含高效抗胆碱药和胆碱酯酶重活化剂,临床应用后,结果表明,收治的1053例急性中毒病例中,轻、中度中毒病例共675例,新疗法治疗425例,传统疗法治疗250例,全部洽愈;重度中毒378例,新疗法治疗255例,治愈242例(94.9％),死亡13例(5.1％),传统疗法治疗123例,治愈72例(58.54％),死亡51例(41.46％),反跳率:新疗法为1.96％,传统疗法为14.6％;而且,住院天数和医疗费用新疗法也比传统疗法有明显降低。以上几项指标,经统计学处理均有显著性意义
This article reports the new treatment of acute organophosphorus pesticide acute toxicity in Hebei Province in 1993, which is a new therapy based on phosphate solution and compared with traditional therapies based on a large amount of atropine. Phosphate solution needle is a compound preparation developed by Institute of Toxicants and Medicines, Academy of Military Medical Sciences, containing highly effective anticholinergic drugs and cholinesterase reactivator. After clinical application, the results showed that among 1053 cases of acute poisoning, There were 675 cases of moderate poisoning, 425 cases of new therapy, 250 cases of traditional therapy, all of them were cured; 378 cases of severe poisoning, 255 cases of new therapy, 242 cases (94.9%) were cured and 13 cases died (5.1%), 123 cases were cured by conventional therapy, 72 cases were cured (58.54%) and 51 cases died (41.46%). The rebound rate was 1.96% for new therapy and 14.6% for traditional therapy. Moreover, Therapy has significantly reduced. Several indicators above, the statistical analysis have significant significance