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目的对无创通气应用于急诊慢性阻塞性肺病(COPD)急性加重期患者的治疗效果进行分析。方法 2007-10-2009-11中国医科大学附属第一医院急诊就诊的COPD急性加重期患者87例,随机分成标准治疗组和无创通气组。无创通气组在标准治疗的基础上加用BiPAP呼吸机。观察两组气管插管率和治疗后6 h的血气变化。结果无创通气组治疗后血气指标PH、PaCO2、PaO2和标准治疗组相比均有显著改善(P<0.05),且气管插管率低于标准治疗组(P<0.01)。结论无创通气对急诊COPD急性加重期患者有较好的治疗效果。
Objective To analyze the curative effect of non-invasive ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods A total of 87 patients with acute exacerbation of COPD from the First Affiliated Hospital of China Medical University from October 2007 to September 2009 were randomly divided into standard treatment group and non-invasive ventilation group. Non-invasive ventilation group based on the standard treatment with BiPAP ventilator. The changes of tracheal intubation rate and blood gas 6 h after treatment were observed. Results Compared with the standard treatment group, the blood gas indexes PH, PaCO2 and PaO2 in non-invasive ventilation group were significantly improved (P <0.05), and the intubation rate was lower than the standard treatment group (P <0.01). Conclusion Non-invasive ventilation has a good therapeutic effect in patients with acute exacerbation of COPD.