作者认为细胞免疫是扁平苔藓的基础,体液免疫不是其起因。慢性活动性肝炎和原发性胆汁性肝硬化患者易发生扁平苔藓,而不少的扁平苔藓患者存在肝功能检查异常,慢性活动性肝炎的发病率也较正常人群高。治疗原发性胆汁性肝硬化的常用药D-青霉胺可引起苔藓样反应并可加重原有扁平苔藓损害。作者报告了一病例:患者女性,80岁,白种人。1982年确诊为原发性胆汁性肝硬化。实验室检查碱性磷酸酶404 IU(正常<150,下同)、谷丙转氨酶85 I U(<35)、总胆红素0.5μmol/L(<1.1)、抗线粒体抗体效价800(<25).最近检查皮肤黄痘,肝肋下2cm 质软,无压痛,双下腿有散在搔痒、糜烂病损。口腔粘膜出现糜烂相同有白色斑 The authors believe that cellular immunity is the basis of lichen planus, humoral immunity is not the cause. Chronic active hepatitis and primary biliary cirrhosis patients prone to lichen planus, and many patients with lichen planus abnormal liver function tests, the incidence of chronic active hepatitis than the normal population. D-penicillamine, a commonly used medication for the treatment of primary biliary cirrhosis, causes a moss-like response and aggravates pre-existing lichen planus lesions. The authors report a case: patient female, 80 years old, Caucasian. In 1982 was diagnosed with primary biliary cirrhosis. The laboratory tests included alkaline phosphatase 404 IU (normal <150), alanine aminotransferase 85 IU (<35), total bilirubin 0.5 μmol / L (<1.1), anti-mitochondrial antibody titer 800 ) Recently, check the skin of chicken pox, liver ribs 2cm soft, no tenderness, both legs have scattered itching, erosion lesions. Oral mucosal erosion appear the same white spots