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作者报告2例格林一巴利综合征(GBS)均起病于水痘一带状疱疹之后,观察了血液T淋巴细胞亚群的变化,指出水痘一带状疱疹感染是GBS重要而罕见的触发因素。例1,男,4岁。水痘皮疹消退8天后出现腿痛、四肢瘫痪,肌腱、跖反射消失。腕、膝以下皮肤感觉缺失,跖关节位置觉障碍。正中神经肘-腕段和腓神经腓-踝段运动神经传导速度减慢为32米/秒和22米/秒、脑脊液(CSF)白细胞12个/μ1,蛋白含量1.83克/L。血清及CSF水痘一带状疱疹病毒补体结合试验阳性,免疫萤光检查见CSF细胞内含有水痘一带状疱疹抗原。急性期外周血中抑制T淋巴细胞显著减少,辅助T细胞轻度减少,而CSF中正常。一月后血液中辅助/抑制淋巴细胞比值恢复正
The authors report that changes in blood T-lymphocyte subsets were observed after two cases of GBS were present in varicella-zoster. It was pointed out that varicella zoster infection is an important but rare trigger for GBS . Example 1, male, 4 years old. Chickenpox rash subsided after 8 days of leg pain, limb paralysis, tendon, plantar reflex disappeared. Wrist, knee below the skin feel missing, plantar joint position disorders. Medial nerve elbow - wrist and peroneal nerve - peroneal - ankle motor nerve slows to 32 m / s and 22 m / s, cerebrospinal fluid (CSF) leukocytes 12 / μ1, protein content of 1.83 g / L. Serum and CSF chicken pox Herpes Zoster virus complement fixation test positive, immunofluorescence see CSF cells contain a chicken pox Herpes Zoster antigen. Acute phase of peripheral blood suppression of T lymphocytes was significantly reduced, helper T cells decreased slightly, while the normal CSF. After 1 month, the blood support / suppression lymphocyte ratio was positive