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1985年1月19日,美国俄亥俄州一位23岁的男性大学毕业生,在他的左手中指上有一值得注意的溃疡。一个月以前,他在圣比来斯岛、巴拿马的丛林中游览时,曾被许多昆虫叮咬过。尽管口服红霉素,而溃疡变得更大了。2月20日,这个大学生因2×2cm的顽固性溃疡长在靠近指关节处,被收进一个地方医院。溃疡处淋巴管扩张不明显。从溃疡边缘处取活组织检查,显示大量的淋巴细胞浸润。作细菌、真菌培养,均为阴性。对该患者使用了口服四环素、静脉注射新青霉素以及伤口引流。
On January 19, 1985, a 23-year-old male college graduate in Ohio, United States, had an ulceration note on his left middle finger. A month ago, he was bitten by many insects while touring the jungle in Sancti Petri, Panama. Although oral erythromycin, ulcers have become larger. On February 20, the college student was admitted to a local hospital for obstruction of 2 × 2 cm of stubborn ulceration near the knuckles. Lymphatic dilatation at the ulcer is not obvious. Biopsies were taken from the edge of the ulcer and showed extensive lymphocyte infiltration. For bacteria, fungal culture, are negative. Oral tetracycline was administered to this patient, intravenously injected with penicillin and wound drainage.