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The hypoglycemic effects of crude polysaccharides extracted from five medicinal fungi were evaluated using alloxan-induced diabetic mice.High(1 g/kg)and low(0.5 g/kg)doses of polysaccharides extracted from Cordyceps taii and C.memorabilis caused significant(P<0.01)decreases in mice blood sugar levels.Polysaccharides from Ganoderma lucidum and C.militaris fruit bodies both exhibited weak hypoglycemic effects at significance levels of P<0.01 and P<0.05 for high and low doses,respectively.Polysaccharide extracted from mycelium of a Phellinus sp.was significantly(P<0.05)hypoglycemic at higher dose levels but lower doses had no effect.
The hypoglycemic effects of crude polysaccharides extracted from five medicinal fungi were evaluated using alloxan-induced diabetic mice. High (1 g / kg) and low (0.5 g / kg) doses of polysaccharides extracted from Cordyceps taii and C. memorabilis caused significant (P <0.01) decreases in mice blood sugar levels. Polysaccharides from Ganoderma lucidum and C. militaris fruit body both both show weak hypoglycemic effects at significance levels of P <0.01 and P <0.05 for high and low doses, respectively. Phellinus sp. Was significantly (P <0.05) hypoglycemic at higher dose levels but lower doses had no effect.