目的 :了解梨状窝癌 (pyriformsinuscarcinoma ,PSC)较恶劣的生物学行为 ,掌握其易向邻近组织、器官侵犯的特性 ,手术治疗是头颈外科领域的一个难题。研究PSC向邻近组织的侵犯规律。方法 :采用连续切片的方法对梨状窝癌术后离体标本进行组织病理学研究。结果 :喉软骨中甲状软骨最易受侵犯 ,其内壁受侵的频度最高 ;PSC对喉软骨的挤压推进式侵犯明显多于浸润破坏式。结论 :喉软骨和软骨膜是抵抗肿瘤侵犯的解剖屏障 ;甲状软骨的下缘、后缘受侵可导致甲状腺被侵犯 OBJECTIVE: To understand the poor biological behavior of pyriform invaginal carcinoma (PSC) and to study the characteristics of its susceptibility to adjacent tissues and organs. Surgical treatment is a difficult problem in the field of head and neck surgery. To study PSC violations of neighboring organizations. Methods: The histopathological study of isolated specimens of pear-shaped carcinoma after operation was performed by serial sections. Results: Thyroid cartilage was the most vulnerable to thyroid cartilage, and its inner wall was the most frequently infiltrated. Compressive propulsive invasion of laryngeal cartilage in PSC was more severe than infiltration rupture. CONCLUSIONS: Laryngeal cartilage and cartilage are the anatomic barriers against tumor invasion; the inferior and trailing edges of thyroid cartilage can lead to the invading of the thyroid