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我们对57例难治性充血性心力衰竭患者,在给予临床休息、强心、利尿和血管扩张剂等常规治疗的基础上,加用β阻滞剂—美多心安,取得了满意的疗效,现报告如下: 1 资料与方法 1.1 临床资料 本组57例均为经住院进行系统常规抗心力衰竭治疗仍无效的难治性心力衰竭患者,其中男44例,女13例。年龄23～65岁,平均44.9岁。心衰病程2～21年。心功能(NYHA分级)Ⅲ级25例。Ⅳ级32例。扩张型心肌病40例,肥厚型心肌病2例,风心病12例,先心病3例。心率≥100次/分45例,≤100次/分,12例。 1.2 治疗方法 原用强心利尿剂不变,在常规治疗基础上加用美多心安。首次剂量6.25～12.5mg,一日三次。三天后视病情逐渐增至25～50mg,最大剂量不超过100mg/日。4～8周为一疗程。
We 57 patients with refractory congestive heart failure, given clinical rest, cardiac, diuretic and vasodilator and other conventional treatment, based on the addition of β-blocker - Metoprolol, and achieved satisfactory results, Now report as follows: 1 Materials and Methods 1.1 Clinical data 57 patients in this group were admitted to hospital for treatment of patients with conventional heart failure is still refractory heart failure patients, 44 cases were male and 13 females. Age 23 to 65 years old, average 44.9 years old. Heart failure course of 2 to 21 years. Cardiac function (NYHA grade) Ⅲ grade 25 cases. Ⅳ grade 32 cases. Dilated cardiomyopathy in 40 cases, hypertrophic cardiomyopathy in 2 cases, rheumatic heart disease in 12 cases, 3 cases of congenital heart disease. Heart rate ≥ 100 beats / min 45 cases, ≤ 100 beats / min, 12 cases. 1.2 The original method of constant cardiac diuretic unchanged, based on conventional treatment with the United States and more peace of mind. The first dose of 6.25 ~ 12.5mg, three times a day. Three days later the condition gradually increased to 25 ~ 50mg, the maximum dose does not exceed 100mg / day. 4 to 8 weeks for a course of treatment.