盐酸硫胺注射液在久貯后常有变色或沉淀情形。其浓度越高的越容易发生上述情形并且越严重。到目前为止,完全稳定不变的注射液尚不易得。现将本人从事这一工作的体会写出,如有不妥的地方请大家指正和补充。原料:——我们所用过的盐酸硫胺原料中,有的是开始结块并呈盐酸的刺激臭气,溶解后溶液显黄色或微黄色,间或也有无色的。但不论溶液有色或否,都呈轻微的浑浊。这样的原料就很难保证成品的稳定性。所以应特别注意,这是决定产品优劣的主要关键之一。在选择原料时,牌号只可能考,不宜依赖。其 Thiamine hydrochloride injections often discolor or precipitate after long storage. The higher the concentration, the more likely the above situation occurs and the more severe it is. So far, completely stable injections are not yet available. Now I will write my own experience in this work. If anything is wrong, please correct me and supplement it. Raw materials: Some of the thiamine hydrochloride raw materials we use are stimulating odors that begin to agglomerate and appear as hydrochloric acid. After dissolution, the solution appears yellow or yellowish, and there is also colorless. However, no matter if the solution is colored or not, it is slightly turbid. It is difficult to guarantee the stability of the finished product with such raw materials. Therefore, special attention should be paid to this, which is one of the main keys to determine the pros and cons of the product. When selecting raw materials, the grades may only be tested and should not be relied upon. its