微囊藻毒素(Microcystin)是世界各地水华中存在最普遍、危害最严重的一类藻类毒素,对环境和人类健康具有极大的危害性。以往研究表明,微囊藻毒素作为一种特异性的肝脏毒素,对细胞内蛋白磷酸酶具有强烈的抑制作用,表现为诱导细胞凋亡和促进肿瘤发生的双重毒性效应。本文简要综述报道微囊藻毒素诱导细胞凋亡和促进肿瘤生成双重毒性作用的研究进展。 Microcystin is one of the most common and harmful algal toxins in the world, which is harmful to the environment and human health. Previous studies have shown that microcystin as a specific liver toxin, has a strong inhibitory effect on intracellular protein phosphatase, showing dual toxic effects of inducing apoptosis and promoting tumorigenesis. This review summarizes the progress reported on the dual toxicity of microcystin-induced apoptosis and tumorigenesis.